Wimbledon was left without the two best players in the world according to ATP Rankings.
Djokovic had received repeated on-court treatment for a shoulder problem during the tournament, but confirmed "it's the elbow that already keeps bothering me for over a year and a half actually".
The victor of the Federer-Berdych match will clash in the final with either Marin Cilic or Sam Querrey, who downed an injured Andy Murray.
Raonic said after the match that Federer is moving well, but that's not the only thing he has going for him.
But let's start from the beginning.
Wimbledon comes as the ideal opportunity as the might even regain that world no.1 spot in the process or at least keep a close eye to Andy Murray, Rafael Nadal or #Roger Federer.
"I kept doing everything with my physiotherapist, and physiotherapist of ATP, what we possibly could to try to recover it and get it into the state where I'm actually able to perform".
On the other hand, Sam Querrey, the victor, was absolutely thrilling after the match.
"It's not a time and place for me to talk about the details", Djokovic said after pulling out while trailing 7-6 (2), 2-0. "I thought I raised the level of tennis", said Djokovic after making the second week without dropping a set.
Wimbledon continues with the men's singles quarterfinals on Wednesday.
The American will face Marin Cilic, who beat Gilles Muller.
Querrey bounced back in the fifth set, breaking Anderson to lead 4-2 and seeing another match point at 5-2.
"I'm very pleased with the way I've felt, the way I've played". Here, there are many of us who have won a lot in our careers, who have a lot of important history behind us.
Top-ranked Andy Murray also won, beating Benoit Paire 7-6 (1), 6-4, 6-4 on Centre Court.
He hasn't won one since.
"It's unfortunate I have to finish the Wimbledon grand slam this way", Djokovic said.
"The courts, honestly, are not that great this year and many players feel the same", the Serb said after advancing to his 39th grand slam quarter-final.
Rain began to fall on Tuesday about 30 minutes before Djokovic and Mannarino were to begin, and as others were suspended, they played the first match of the tournament under the roof.
He also winced following the first serve of his third and final match point - a 24-shot rally that ended when Mannarino's forehand went into the net.
This was the second time that Tomas Berdych defeated Djokovic here at All England Club.
Murray suggested after his win that Wimbledon should look at staging more than three matches a day on the showcourts. On Court No. 1, Rybarikova was playing Vandeweghe.
"It was a long day, tough day, waiting for the entire day to get on the court".